Seals, o-rings, tip holders, tip ejectors and the volume adjustment knobs can easily be changed in your own laboratory without affecting the calibration of your pipettes There are however a number of parts that when changed can alter the pipettes calibration. These parts include the piston and piston assembly, friction o-ring, operating rod and volumeter. When these need changing it is best to return your pipettes to your service provider for replacement and pipette re-calibration.
Prevention is better than cure.
It is recommended that you check your pipettes daily before use and establish a routine for basic servicing. There are a number of basic care checks for your pipettes that can be performed in your own laboratory to maintain correct functionality in between full servicing. These include a simple functionality check and a visual leak test.